Effects of chlorpromazine and trifluoperazine on the activity of chronic schizophrenics.

نویسندگان

  • I H Jones
  • N Pikler
چکیده

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Phenothiazines inhibit cholesteryl ester formation in J 774 monocyte-like cells.

The effect of phenothiazines (trifluoperazine and chlorpromazine) on cholesteryl ester metabolism has been investigated in J 774 mouse monocyte-macrophages. The incorporation of oleic acid into cholesteryl ester and the activity of acylcoenzyme A: cholesterol-O-acyltransferase were strongly decreased in cells pretreated for 24 h with trifluoperazine or chlorpromazine. Furthermore, trifluoperazi...

متن کامل

A double-blind trial to investigate the effects of Thorazine (Largactil, chlorpromazine), Compazine (Stemetil, prochlorperazine) and Stelazine (trifluoperazine) in paranoid schizophrenia.

IN the early phenothiazine literature the ataractic properties of Thorazine in the control of disturbed, hyperactive schizophrenics were described (Kurland, 1955; Hall and Dunlap, 1955; Lehmann, 1955). Kurland (1955) gives an excellent description of the powerful activity ofThorazineinthis sphere, namely the control of hyperkinesis and hostile, aggressive behaviour; however, he found that there...

متن کامل

P-58: Evaluation of Ovarian Toxicity Effects of Chlorpromazine in Female Rats

Background: Elevations in serum prolactin levels (hyperprolactinaemia) are a common side effect of conventional antipsychotic treatments. The main objective of this study was to consider the effects of the antipsychotic drug chlorpromazine (CPZ) in female rats reproductive system and to examine the relationship between the effects on reproductive organs and hormone concentrations. Materials and...

متن کامل

Neuropsychological differentiation of chronic schizophrenia.

Four groups of 20 each (chronic brain-damaged schizophrenics, chronic non-brain-damaged schizophrenics, chronic non-brain-damaged with "acute" exacerbation, and control subjects) were individually administered Form I of the Luria Nebraska Neuropsychological Battery (LNNB). Control subjects scored significantly lower than all clinical groups on all scales except for the chronic non-brain-damaged...

متن کامل

Inhibition of hormone-sensitive adenyl cyclase by phenothiazines.

Chlorpromazine (3 x 10(-4)M) prevents the stimulation of adenyl cyclase activity in thyroid membranes produced by thyrotropin and prostaglandin, ACTH stimulation of adenyl cyclase in adrenal tissue, and glucagon- and epinephrine-stimulation of adenyl cyclase activity in liver. Baseline activity is unaffected. Parathyroid hormone stimulation of kidney preparations was not inhibited under these c...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The British journal of psychiatry : the journal of mental science

دوره 119 552  شماره 

صفحات  -

تاریخ انتشار 1971